Polynucleotides

Polynucleotides are primarily derived from salmon DNA, making them natural, biocompatible, and biodegradable. According to international Facial Aesthetics Trainer, Dr. Bob Khanna, polynucleotides act as "food or medicine for cells," promoting collagen and elastin production while enhancing the skin’s extracellular matrix (that's the vital structural layer that keeps skin youthful and firm!).

While different manufacturers might refer to polynucleotide treatments as biostimulators, biofillers, or biorevitalisers, they all revolve around this powerful anti-ageing ingredient.

Traditional anti-wrinkle treatments (like Botox) typically last 3-4 months. Polynucleotide treatments, on the other hand, can last between 6-12 months, with ongoing improvements to skin quality long after the initial effects.

Unlike dermal fillers that simply plump the skin temporarily, polynucleotides regenerate skin at the cellular level. They boost hydration, collagen production, and skin elasticity. Some treatments that we offer, such as Pluryal Densify, combine polynucleotides with hyaluronic acid for added volume.

While most anti-ageing treatments take months to show improvements, you can see visible results from polynucleotide treatments within approximately 3 weeks, with full effects becoming more apparent over several months. The skin will gradually improve in texture, firmness and hydration.

When combined with hyaluronic acid, the effects can be immediate!

Usually 2-3 treatments, 4 weeks apart are required to achieve optimal results. A top up every 12 months is recommended to continue to enjoy the effects.

At DrBK, we offer optional numbing cream before the treatment for those that are sensitive to needles. However most patients, particularly those who are used to 'botox', fillers or microneedling, may feel they do not require numbing at all.

We offer polynucleotide treatments at both of our locations in Reading (Queens Road) and London (Harley St). Book now.

At DrBK Reading and Harley St, we offer a range of polynucleotide treatments tailored to different skin and hair concerns. Here are the key options:

1) Pluryal® Silk

One of the most popular polynucleotide treatments at DrBK Reading & Harley St is our Pluryal Silk. This is a skin densifier with polynucleotides, designed for delicate areas like under the eyes (to reduce dark circles), around the mouth, hands, chest, and even postpartum stretch marks on the abdomen. Perfect for those seeking to target early signs of ageing in sensitive areas.

2) Pluryal® Densify

This repair treatment combines polynucleotides, hyaluronic acid, and mannitol (an antioxidant) to restore lost volume and improve skin texture. Ideal for rejuvenating dull, damaged skin, or fatigued areas of the face—except for the under-eye region.

3) Pluryal® Hair Density

Our latest solution for hair loss, Pluryal Hair Density nourishes the scalp and promotes hair regrowth. It’s effective for thinning hair, androgenic alopecia, post-transplant recovery, and temporary hair loss conditions like telogen effluvium.

PRP is often used in conjunction with polynucleotides for optimal results.

PRP (platelet-rich-plasma) treatment involves using a patient's own blood to promote cellular healing. It involves collecting a small amount of blood from your arm (similar to a routine blood test) which is then placed in a centrifuge which separates platelets from other blood cells. The plasma-rich-platelets are then injected into the affected area. PRP contains growth factors to help our bodies heal and regenerate.

Using the Pluryal Mesoline Range; Specifically developed products that work to target a variety of skin complaints.

Following topical application, the products are fed deeper into the skin using a mesoline roller (otherwise known as microneedling), which introduces microscopic holes in the skin to allow the quantities of volume, hydration, vitamins and minerals into the skin (or scalp) to help it rejuvenate and repair itself.

Products include;

• Antiox: Antioxidant action for damaged and dull skin. Fights premature ageing.
• Clear: Designed to regulate skin sebum, reduce acne and other skin imperfections. Also reduces inflammation of the skin.
• Shine: Enriched with Vitamin C to reduce blemishes and reduce brown spots/pigmentation.
• Tight: Lifting action to tighten skin and reduce dilated pores.
• Refresh: Revitalising action to target dullness and lack of elasticity.
• Radiance: Brightening action to reduce dark circles/pigmentation.